Through various types of research, there are many questions about how Sirtuins affect the aging process. There have been papers recently published in Nature which offer information about the biology of aging. These papers though are contradicting each other. One is about the understanding of the biology and the other is about how it can be manipulated with the anti aging procedures offered.
The gene that is being talked about is Sirtuins, and it is often referred to as Sir2. The possibility of increasing Sir2 in the body has been found to increase longevity in various types of research animals. This has gained the attention of scientists as well as people that would love to look younger. There are various clinical studies in the works right now that involve the injections of Sir2 on humans.
Leonard Guarente discovered that by changing Sir2 slightly, the life span of yeast could be extended. This was later replicated in flies and worms. It was also the basis for millions to be spent on research for various drugs that could offer humans the same benefits. This all began over a decade ago, but the technology today has allowed the research to move forward.
Yet not all scientists believe that Sir2 is the answer when it comes to slowing down the aging process. They believe that there was very little improvement for mice and so that means it may not work for humans. Many experts believe that with flies and worms there were too many variables that could account for the anti aging results.
Only time will tell if Sir2 is the answer to slowing down the aging process or not. The results from the human clinical trials are still years away. Not only do they need to explore the benefits, but also any possible side effects that the injections of Sir2 could trigger.
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